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dapsone, does it work?
Jan 27, 2004

Dr. Dave,

Does this drug, Dapsone, work? If so what exactly is it supposed to do and does it do this?

Martin

Response from Dr. Wohl

Dear Martin-

Dapsone is an antibiotic that is used mostly as an alternative to trimethoprim/sulfamethoxazole (Septra or Bactrim) to prevent or treat Pneumocystis carinii pneumonia (PCP).

People with allergies to sulfa containing medications such as Septa and Bactrim can usually tolerate dapsone. An important point regarding dapsone is that some people with a genetic deficiency in an enzyme called G-6PD can develop a type of anemia when they take dapsone in which the red cells get destroyed. Most clinicians check G-6PD levels during the initial visit.

Dapsone works and is a godsend for those with sulfa intolerance.

Thanks - DW



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