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with t-1249 dead, now what?
Jan 9, 2004

Dr. Young,

With the approval of t-1249 put on halt in clinical trials what is the next agent in the pipeline that is working to take it's place?

Ruben

Response from Dr. Young

The development of T1249 has been halted, not it's approval, per se.

There are other compounds in development, like CCR5 inhibitors that might work in complementary ways-- these are still in very early stages of clinical discovery; until we see more advanced studies, the prevention of HIV entry into cells will still depend on the existing (and FDA-approved) fusion inhibitor, enfuvirtide (T-20, Fuzeon). BY



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