where clinicial trials for facial lipoatrophy: no meds?
Oct 20, 2003
I am have temple wasting due to hiv disease and take no meds. I would like to enroll in a clinical trial for facial lipoatrophy for people who get temple wasting without meds? Where is the question, go any suggestions?
Response from Dr. Wohl
Some people with HIV do develop wasting even though they never have taken HIV medications. The wasting syndrome that occurs with HIV itslef is usually a wasting of fat AND muscle. Overall body weight falls (this is why AIDS was first called Slims Disease in Africa).
Lipoatrophy accompanying HIV therapy, on teh other hand, is characterized by wasting only of fat. Overall body weight stays about the same.
There have been clinical studies looking at wasting syndrome. These tend to try to increase weight. Androgens, growth hormone, appetite stimulants, thalidomide have each been studied. Nowadays it is difficult to enroll in such studies as there are few cases in the US or Europe of wasting syndrome circa the 1980s. DW
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