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TRAIL
Oct 9, 2003

Dear Dr.

What is the therapeutic value of TRAIL and do you think it will ever be used in treatment?

Response from Dr. Pierone

TRAIL is the acronym for tumor necrosis factor-related apoptosis-inducing ligand. It surfaced in early basic (test tube) research about 2 years ago as a potential immune-based target. Its look likes Immunex originally developed it and they have been acquired by Amgen. I checked the Amgen web site and was not able to find any mention of it in their posted information. If you know any more (original references) I can look into it further.



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