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VIral load understanding
Oct 6, 2003

Dr. David,

If your viral load starts to go up wouldn't you definitely start producing antibodies, and aren't the tests used today in all areas sensitive enough to pick up very small numbers of antibody production?

Is there ever a case where the antibody production does not happen in measurable amounts in response to viral load increase?

Thanks!

Response from Dr. Wohl

Right, first the virus enters the body and reproduces - creating the highest levels of virus in the blood that will ever exist in that person. The body then reacts by making antibodies which, like many antibodies we make, stick around for a long time (decades-the life of the individual). When the viral load declines due to therapy, the antibodies persist and do not vanish - acting as a lifelong marker of previous HIV infection. DW


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