|abnormal immune system
Sep 26, 2003
good afternoon dr
due to abnormal immune system, a person co-infected with hiv and hep b has shown to take longer to build an immune response to hiv's presence in the body. we know this has happened in rare cases for sure.
what about an overproduction of cortisol? with its destructive properties, is it plausible that hypercortisolism could block or disrupt production of not only hiv infected t cells, but also destroy b cells in the blood before they had the chance to form, or destroy enough of them to remain seronegative on EIA/ELISA?
Response from Dr. Pierone
With excess production of cortisol (very rare condition) the immune response to HIV would still occur with antibody production and positive EIA/ELISA.
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