hiv lifecycle question
Sep 18, 2003
Did scientists find the gene that causes hiv to mutate under drug pressure? If so are there drugs under investigation that turn this gene off?
Response from Dr. Young
yes; HIV has a very high intrinsic mutation rate because of the way that ir reproduces-- the gene that is responsible for this is the reverse transcriptase. Turns out though, that so long as you're able to prevent replication, that it probably doesn't matter as much what you use to shut this down.
That is to say that we do have drugs that prevent replication in the majority of therapy naive persons, namely, antiretroviral medications or HAART. BY
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