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life expectency becoming less because of age
Sep 15, 2003

Dr Gerald Pierone good morning . I am the same person from India. Doctor I am doing well with my meds . I started 30 days back and have not missed even pill . doctor my only worry is I am on d4T which I am reading in the other forums of body is that it will have severe side effects Doctor can I discontinue after 6 months when my vl and cd4 counts improves. or i continue further time. Is there any way to notice in advance the side effects. doctor I am 42 years male . If I continue good life styles and meds i will also will have the normal 30 years expectency or will it be less because of my age . doctor since iam already 42 years is there any special cares ihave to take . doctor please help me regards

Response from Dr. Pierone

Yes, I know you are the same person from India. Dr. Young and I were discussing your case over breakfast this morning in Chicago (we are covering ICAAC for If you don't mind, we have decided that next time we visit India we plan to stay at your house since we have gotten to know you fairly well. It should work out fine, you will be able to ask us and whatever you like about HIV issues and we can save on the expensive hotel room rates. Don't worry, we will give you advance notice.

OK, on to your questions. Don't worry so much about d4T (stavudine, Zerit). Generally, if side effects do develop, they tend to occur after several years. I have patients that I have been following on it ever since it was released and they have had no problems. You should look out for numbness in toes and feet (peripheral neuropathy) and thinning of the face (loss of cheek fat). When tenofovir (Viread) becomes available in India it would be reasonable to change Zerit to this medication.

I would not suggest you stop treatment after only 6 months. Treatment of HIV is a long-term endeavor. Though studies are being done on structured treatment interruption (STI) to minimize exposure to medications and reduce long term side effects so stay tuned. See my coverage of STI debate at IAS meeting in Paris here.

Finally, yes your prognosis is excellent, especially since you are diligent about taking your medications. I really wish more of my patients here in the States were as good about taking medications are you are. Best regards. GP

why Kaletra?
When to stop??

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