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choosing the right meds?
Sep 11, 2003

what is considered the gold standard ?

Response from Dr. Pierone

There is not a gold standard for HIV treatment. There are a number of treatment guidelines that have been developed by different expert panels they are quite helpful, but are not uniform. In any case, the standards of care change regularly because of new agents and new studies of existing agents.

In the U.S. the most common regimen for treatment-nave patients is a non-nucleoside reverse transcriptase inhibitor - nevirapine (Viramune) or efavirenz (Sustiva) based combination. A dual nucleoside (or nucleotide) backbone like lamivudine (Epivir) and tenofovir (Viread) is commonly used with the non-nucleoside. Protease inhibitor-based regimens may be used first but there has been a trend away from this strategy because of metabolic side effects that they may produce. Likewise, it is less common to see triple nucleoside therapy being used first because of studies that have shown somewhat lower potency.

If you would like to really delve into the subject this link will take you to the recently updated DHHS treatment guidelines.


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