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ELISA's/follow up question
Sep 3, 2003

Many thanks for answering my question on ELISA's and the strains of HIV they detect.

You mention using a Roche 1.5 test for suspected non B infection (which is my case). I had the Roche 1.5 test and a negative result. But I understand that the Roche 1.5 test only claims to detect subtypes A through G of HIV-1 M group. I was exposed where there are additional subtypes in the M Group (H, I and J). How do I get tested for these? I had a serious exposure, have a lot of bad symptoms and rapidly falling CD4 count and percent - is there an ELISA test or broader nucleic acid test (than the Roche 1.5 or bDNA) that would pick up all the M Group subtypes? I have been tested for O Group antibodies and that was negative, so it is the non B M Group subtypes that are my problem.

Many thanks.

Response from Dr. Pierone

Hello, I will need to do some research to answer your question. This question is better suited for the "understanding your labs" forum and I will follow up on it there. I have a few questions for you that help though. Where were you when you had the exposure and how long ago? What were your symptoms and CD4 counts and ratios? Thanks, GP


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