|ELISA/good for all strains of HIV?
Aug 29, 2003
Does a negative ELISA test after 6 months rule out infection with any subtype of HIV-1 Group M? Or is the ELISA just good for detecting antibodies to the main (major) strains of HIV-1? If this is the case, how can one be tested if one had possible exposure to rarer strains...subtypes of HIV followed by bad symptoms, and falling CD4 numbers....?
| Response from Dr. Pierone
The standard ELISA test is very good for determining infection with the clade B strains of HIV that account for the vast majority of infection in the U.S. It is less reliable for establishing a diagnosis for group O and non-subtype B virus. If there is a reason to suspect infection with one of these strains (recent trip to Africa with unprotected sexual exposure) then a Amplicor (version 1.5) viral load test can be done to detect other strains. Hope this helps.
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