|i don't care what anyone says, dave, i think you're alright!
Aug 25, 2003
why do i have to be funny to get a response from you? anyway, thanks for reading this. what are your thoughts on the relationship between heightened cortisol levels and progression of hiv disease?
any thoughts on steroidogenesis inhibitors?
| Response from Dr. Wohl
Actually you don't, but it helps.
What you are driving at, I believe, is the theory that cortisol (a chemical made in our adrenal glands) is made in excess in the setting of HIV infection and used inside of T-cells to do the virus' dirty work.
Proponents of this theory and similar ones in which HIV proteins act like cortisol, suggest that anti-cortisol drugs may help fight the effects of HIV.
We are now at the outer limits of my knowledge about this. I do know that some clinical studies of such agents are underway. DW
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