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Doctor Young
Aug 6, 2003

Hi

For someone who finds meds that their strain of virus is sensitive to is it unusual for the virus to become resistant to the meds if that person takes every dose? I know that the problem with monotherapy in the 90's brought on rapid resistance butwhat about aherent people on HAART?

Response from Dr. Young

In general, it would be unusual for the virus to become resistant to a sufficiently potent treatment regimen that is 100% adhered to.

There is data that treatment failures do occur more frequently among persons with lowest CD4 cell counts and highest viral loads, suggesting that this statement is not an absolute one, but a pretty good estimate, particularly based on studies of directly observed therapy, where treatment failures were very rare. BY



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