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Aug 4, 2003

What is "agammaglobulinemia" and what specific blood tests are used to diagnose it? How is it treated and how would it effect the course of HIV disease/symptoms?


Response from Dr. Young

Agammaglobulinemia is a condition where the body produces insufficient amounts of antibodies. It can be diagnosed by relatively simple blood tests.

The interaction between HIV and agamma is probably not well characterized, since, fortunately, it is quite rare to see both. Importantly, it can be one of the rare situations where someone is HIV infected with positive HIV antibodies, then with the loss of all antibody production (due to agammaglobulinemia), the HIV antibody test can potentially revert back to negative, even though the virus is still around. BY

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