what do you think
Jul 8, 2003
does this theory seem solid to you? ive been hearing alot about this new drug?
Response from Dr. Pierone
I reviewed the web site that you referenced and the theory behind this agent is interesting. They have linked a toxin of some kind to gp120. The idea is that if you give this combination to persons with HIV it may target and kill the B lymphocytes that produce antibodies to gp120. If so, it might prevent some of the immune destruction of T cells that are coated with gp120, but not infected with HIV.
The site makes some wildly optimistic predictions about the potential for this agent in humans and that is a major concern. For example: "While a person on this drug would still be HIV-positive, he or she should be able to live out a normal life span with a fully functional immune system". Yikes! This is quite a statement to make for a compound that has not yet been tested beyond rats.
Given the incredible diversity and complexity of the human immune system it is nave to assume that one specific immunologic approach like this would be the magic bullet to control HIV.
In summary, this compound is at an extremely early stage of development and has a long way to go before it can be determined if this approach for immune-based treatment will be worthwhile.
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.