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Missed Doses
Jun 26, 2003

A patient recently missed about 6-7 days of antiviral medication due to a mistake in re-filling through a mail-order phatrmacy. Can this make a virus become resistant to medications along with raising viral load and decreasing CD4 count? Any advice/sugestions?

Response from Dr. Young

Usually missing all of your medications (at the same time) does not significantly increase the risk of developing drug resistance (this is why some researchers are experimenting with a week-on/week-off treatment strategy).

The best advice here is to make sure (as much as possible) that you've arranged for your refills prior to the end of the dosing period.

Otherwise, I don't think that I'd worry too much-- just make sure that the viral load stays in the undetectable range within a month or two. BY



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