Jun 21, 2003
If a person was able to find a combo of antiretroviral drugs that fit their schedule and were able to adhere to this combo, would the combo work indefinately if a single dose was never missed?
| Response from Dr. Wohl
Most data demonstrate that once you reach adherence levels above 90% or more, the more adherence the better at keeping HIV under control. In the longest running trial of combo therapy, persons on AZT+3TC+indinavir have remained with viral loads that are undetectable for 7 years. These peopel are very adherent.
So, while absolute adherence does not guarantee a person will have a viral load that becomes and stays undetectable, it increases the chance greatly. Other factors such as the potency of the drug combo, absorbsion of the drugs, perhaps some genetic factors, infection with a resistant virus, also play a role in treatment success. DW
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.