Jun 5, 2003
I asked Benjamin about usefulness of blood transfusions.. and he replied shortly that its not effective since most hiv particles resides in glymph nodes.. well.. that aroused another question.. if it mostly resides in those nodes.. is it anygood removing them?..
And another question Id like to have answer from expert is.. When Cd4 count drops untill patient is susceptible to Opportunistic diseases.. is it possible to pump in more White cells? a high consentration cd4 plasma?
| Response from Dr. Wohl
While these seem like obvious approaches to fight HIV there are several reasons that after 2 decades into the HIV pandemic they are not practiced.
Lymph nodes play an essential role in maintaining health - even in HIV-infected persons. Lymph nodes contain immune cells that fight infections and drain a system of canals that course through the body parallel to veins and arteries. Remove them and you get lots of swelling downstream and even increased risk of infections.
Also, while there is a lot of HIV concentrated in the lymph nodes it is in other places too such as the genital tract, the brain, spleen etc. Caution is advised to those looking to cut HIV out.
Transfusing more T-cells is also problematic since these cells are designed to fight things that are not 'self'. Take someone else's T-cells and put them in another person's body and everything around it is foreign and a target for attack. Not good. Also, this could be like adding wood to a burning fire as T-cells are HIV lunch.
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