Jun 1, 2003
DR., Do you have any experience in your practice with using STIs? If so, how do the results look when examining when they started treatment, as well as their length/type of treatment before the STI. Thank you for your time.
Response from Dr. Young
In general, I don't endorse the use of structured treatment interruptions (outside of clinical trials). I think that there are too many unknowns about safety and resistance to make this a strategy for wide-spread use.
Treatment holidays (or treatment interruptions) are done in some patients with the highest viral loads, particularly among those whose lowest ever CD4 counts were above the current threshold for initiation of treatment (>350). BY
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