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This one is stronger than....
Apr 6, 2003

Dr.CC Thanks for that great answer on Strength and Power. Is there any info on which combo, Nevirapine, Abacavir 3TC. Or Nevirapine Tenofovir, 3TC is better at supressing the virus. Let us say the person is a drug virgin. Thanks, W.

Response from Dr. Cohen

Two similarly great combinations you have listed here. Since nevirapine and 3TC are in both - the question is what's the difference between Tenofovir and Abacavir.

Both are very good medications. Both have a low risk of lipodystrophy based on what we've seen over these years. Both are pretty easy to live on - although perhaps 5% do NOT tolerate abacavir due to an allergic reaction, while this is not a problem for tenofovir. Other than this - they appear to be similarly potent and able to control HIV. They both are powerful -- similar power to the two of them based on what we know. And if there is HIV rebound - these drugs are similar in terms of which mutations that might show up - with some reasonable debate as to which is better able to protect itself from resistance... and a hint that abacavir might be a bit better based on recent studies.

So I'd say at this point - that both are strong, powerful, and important options to consider for those that are, say, drug virgins...

OK, W?



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