|Fusion and entry inhibitors
Mar 13, 2003
Dr. Young: Hi. When several of the fusion and entry inhibitors become a reality for HIV treatment will these agents be taken combination as HAART is today? And will these treatments have a lower toxcidy and resistant profiles than HAART or is it early days yet to perdict the outcome? Thanks for any reply. Justin
| Response from Dr. Young
Thanks for your question.
Fusion (or entry) inhibitors should make their debut in the near future with the release of enfuvitide (nice name, huh--otherwise known as Fuzeon or T-20). The class of medications is exciting from the perspective that many persons with drug resistance should retain full activity of the new class.
Unfortunately, the drug is very expensive (~$20,000/yr), requires twice daily injections and needs to be taken with at least a couple of other HIV medications. Is it less toxic? The large investigations of the drug have shown it to be relatively well tolerated, with the exception of injection site allergic reactions.
As for future medications, this remains the realm of speculation, since what we'd really want is an oral (pill-form) entry inhibitor. Such compounds are in very early stages of investigation, so we can't really tell you about the potentcy or side effect profile. -BY
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Is Rectal Bleeding A Sign Of Acute HIV Infection?
- Is White Tongue An Early Sign Of HIV?
- AIDS Infection Risk Touching An Open Scab
- Can You Catch AIDS From Blowjob From A Prostitute?
- Diarrhea After Receptive Anal Sex Without Condom Does It Mean I Have HIV
- Fatigue After Handjob Worried I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.