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AIDS Vaccine

Mar 9, 2003

How will one tell the difference between antibodies produced in response to an AIDS Vaccine to those produced in reaction to HIV?

Response from Dr. Young

Great question-- the answer will depend on what parts of HIV are used to generate the vaccine.

In general, natural infection generates a variety of antibodies- detected on Western blot testing. By contrast, vaccination with a limited number of viral proteins, should produce only a limited number of antibodies, as measured by the same test.

This is actually how we can readily distinguish between natural- and vaccine-related antibodies to hepatitis B. -BY

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