Feb 11, 2003
I have been off medication for over a year and my viral load has gone up marginally (30,000 now is the highest). The point that is more alarming to me is that my CD4 counts have plummeted (700 a year ago and 300 now). I have resistance to the 'sustiva' class of drugs (sorry if my terminology is off), so they are out. My doctor has recommended Kaletra, Ziagen, and Zerit. My former regimine was Zerit, Ziagen, and Epivir which did quite well (have viral resistence to Epivir now per last Genotype test). Is this a good regimine? I only ask because the former one was fairly side effect free
Response from Dr. Young
Thanks for your question.
It's difficult to answer your question in detail, not having all the nuances to your medical history; nevertheless, the combination of abacavir/stavudine/Kaletra should be an effective next drug regimen for someone with resistance to NNRTIs and lamivudine (3TC, Epivir). As for why not to use stavudine/abacavir/epivir, I would agree not to use this if you have documented resistance to lamivudine, since this might weaken the regimen and cause premature treatment failure.
Either way, the goal is to find a side effect free regimen; I'd work with your doctor to make sure that whatever the next regimen ultimately is, that side effects are acceptable.
Good luck. -BY
P24negative - response
Sustiva causing resistance to other nNRTIs
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.