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Combivir/Viramune
Nov 27, 2002

BY- I am a physician who cares for a good number of HIV patients. I know that Epivir can be dosed at 300mg once daily and that Viramune can be 2 pills once a day. Is AZT able to be taken 600mg once daily so that someone on Combivir/Viramune could take 4 pills just once a day. Thanks

Response from Dr. Young

Thanks for your question. The idea of a once-daily Combivir is, indeed, very attractive. However, this remains in the realm of the very investigational, and I can't yet endorse this as a way to get a once-daily nucleoside backbone.

Undoubtedly, there are other once-daily nucleoside backbones that can be substituted, including the now well studied tenofovir/lamivudine; or the lesser well studied didanosine/lamivudine. Future possibilities (depending on the results of studies) may include abacavir and extended release stavudine.

Thanks again for your question. BY^



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