Re: Re:Adding 1 regimen
Aug 1, 2002
Dear Doctor, Here in our place there is some kind of unclear opinions amongst the concerned physicians, regarding switching of regimen. Well earlier I had asked you about adding a new regimen to a double therapy ( AZT & 3TC). Some of the doctors here says it is okay to add one regimen if the previous regimen are not resistant. Some says atleast two out of three regimen must be changed. Could you please give your comment on this ? PPS: The tests like V/oad, CD4 and resistance here in our place are beyond our reach. Therefore we usually go for the clinical signs. Regards.
Response from Dr. Boyle
If viral load is not available and you cannot document suppression to <50 copies/mL on the regimen the patient is on, then the best thing to do, in my opinion, is to change or add at least 2 drugs and the drugs that elected should preferrably have a different resistance profiles than the antiretrovirals the patient is currently taking. If you add just one drug to a regimen that is "failing" (i.e., not fully suppressive), especially a one point mutation drug (where high levels of resistance develop with only one mutational change), then you are likely to end up with rapid failure of the new drug, which is obviously not what you want.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- What Is The Risk Of Sharing A Razor?
- Dry Cough After Oral Sex On A Woman What Are The Chances Of HIV
- Itchy Vagina After Touching Skin Sign Of HIV AIDS
- Pain In Penis After Having Sex During Period What Are The Chances Of HIV
- Swollen Glands After Anal Sex Without Condom Does It Mean I Have HIV
- Tingling Lips After Sucking Penis Worried I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.