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protein bound
Jun 6, 2002

What does it mean when a drug isaid to be highly protein bound? Can taking proteolytic enzymes(otc) for digestion interfere with p.i. s?

Response from Dr. Young

When drugs circulate in the blood, often, a large proportion of the drug is bound to circulating proteins. However, it is the free (unbound) protein that has chemical activity.

The use of supplemental dietary proteolytic enzymes should have no effect on the level of proteins in the blood, and hence no effect on drugs that are protein bound. BY



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