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May 26, 2002

Which is the most potent na?Which is the most potent nnrti?

Response from Dr. Young

Based on recent data, the most potent nucleoside/tide inhibitor is probably tenofovir (followed by abacavir); the most potent non-nucleoside is efavirenz.

Bear in mind, though, that these studies reflect the drug as monotherapy-- their use in combination therapy may affect potency (either positively or negatively); moreover, durability (where potency meets the proverbial pavement) relates to tolerability and toxicity in addition to potency. BY

Asymptomatic; feeling great! How long should I wait?
acute drug reaction

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