|Herpes and VL
May 16, 2002
I had an acute provial syndrome 1 yr ago. Surprisingly my VL=1,000 and CD4=600. 4 mo. later my VL=1000 and CD4=685. MY HLA type is b27/b27 (courtesy of Bruce Walker). I thought my prognosis would be slow progressor. Now 1 yr later I get tested and cd4=400 VL=170,000! When I got my tests I had a herpes outbreak (which I get 2x/yr). I started meds tonight but had a second re-draw before hand. I took one dose (Kaletra/trizivir). Can herpes cause such an increase and should I stop and wait for my redraw value even though my HSV was not completely cleared up at the time of redraw (4 days after my first draw)?
| Response from Dr. Pavia
Interesting problem. Herpes outbreaks can cause a spike in viral load. In one study that I recall, the average increase was about 1 log, or a 10 fold increase. This would increase your viral load temporarily to about 10,000. However, there was marked person to person variation. Some had little change in viral load with an outbreak, others had fairly large changes. There was a lot of interest in whether suppressing herpes outreaks actually improved outcome, in the "pre-HAART" era.
It is indeed possible that your increase is due to herpes. If you are reluctant to start such an aggressive regimen without knowing for sure what is going on, there is no harm in waiting with your numbers. It may in fact be best to wait until you are several weeks out from the outbreak. I would support this approach, but I would urge you to discuss it with your doctor.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Hair Loss After Handjob Worried I Have HIV
- Itchy Skin After Precum Touching Vagina Sign Of HIV AIDS
- Oral Ulcers After Having Sex During Period Sign Of HIV AIDS
- Pain In Urethra After Oral Sex Form Sex Worker What Are The Chances Of HIV
- Swollen Glands After Anal Fingering Worried I Have HIV
- Does Antihistamine Help Atrophic Vaginitis?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.