Once a day regimen
Mar 11, 2002
I read your article on HIV and Hepatitis.com regarding once daily epivir for HIV http://www.hivandhepatitis.com/hiv_aids.html#022202c
You say "These approvals now make it possible to put together a 3-pill HAART regimen (efavirenz, didanosine, tenofovir) in which all of the pills are dosed once-daily..."
Since tenofovir must be taken with food and didanosine on an empty stomach--doesn't that defeat the purpose of a once a day regimen? You still have to remember to take your pill(s) twice a day. Wouldn't a better choice be efavirenz, didanosine, and epivir?
Response from Dr. Boyle
Yes, efavirenz, didanosine and epivir are a good choice and can be taken all at once. The pharmacokinetic interaction between tenofovir and didanosine is being explored (preliminary data indicate that tenofovir raises didnaosine levels roughly as much as a meal lowers it) and it may be possible to dose the two together with a meal making it a truly once daily regimen.
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.