Dec 24, 2005
What are the 3 most commonly prescribed combinations of first meds now? What drugs go with fosamprenavir? Is fosamprenavir a drug that could be used for a person's first drug treatment?
Response from Dr. Young
Thanks for your post.
If one follows US treatment guidelines, the most highly recommended regimens are AZT/3TC (Combivir) or tenofovir/FTC (Truvada) with either efavirenz (Sustiva, Stocrin) or lopinavir/ritonavir (Kaletra).
Because treatment guidelines often lag behind practice habits, it's important to know that among the nukes, all of the fixed-dose combinations, Combivir, Truvada and abacavir/3TC (Epzicom) are most frequently used, with a nod to the once-daily Truvada and Epzicom in terms of recently initiated combos. Among the PIs, Kaletra's use had declined in recent months in favor of the use of once-daily combos with either atazanavir (Reyataz) or ritonavir-boosted fosamprenavir (Lexiva). The availability of the new tablet formuation of Kaletra will offer yet another lower pill count, once-daily PI option.
We've used fosamprenavir with success for several years-- among treatment-naive patients, the drug has been extensively studied with abacavir and 3TC; studies with other nukes are ongoing. We've used once-daily ritonavir boosted fosamprenavir primarily with Epzicom and Truvada for first-line treatment with excellent results; patients rarely report any significant side effects. The option of once-daily treatment without dietary restriction and minimal impact on lipids (cholesterol) have been attractive to many patients.
I hope this helps, good health to you. BY
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Sore Throat During Seroconversion
- Black Spots After Receiving Oral Sex Worried I Have HIV
- Pain In Balls After Receiving Oral Sex Sign Of HIV AIDS
- White Discharge After Vaginal Sex With Condom Does It Mean I Have HIV
- How Long Does Chlamydia Take To Show?
- Accidental Intake Of A Double Dose Of HIV Medication
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.