I have recently started a regimen of Reyataz, Norvir and Truvada. I have previously been taking vitamin supplements including an antioxidant combination, B complex and 1g Vitamin C. May I continue this vitamin regiment and not interfere with my treatment?

Thanks for your question.

There is a growing appreciation for the potential of supplements and other over-the-counter medications to interact with prescription medications, including antiretrovirals.

In moderation, there shouldn't be any significant interactions between the vitamins that you've listed and your HIV medications. I caution my patients against taking more than 1 gram of vitamin C per day, since this has been shown to alter the metabolism of other protease inhibitors (and might, by inference cause problems for yours). You should be aware that some recent data raised important questions about the effectiveness of antioxidants, though this remains controversial.

Lastly, be sure that you take your current HIV medications with food, and avoid the use of antacids (since these factors also significantly affect the absorption of Reyataz). I always advise my patients to tell me which products they're taking, both prescription and over-the-counter, because of the potential for such interactions.

Good luck, BY