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Lipodystrophy and WastingLipodystrophy and Wasting
           
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Herbal/mineral/comp preparations for muscular wasting & PN
Apr 29, 2004

What mineral/herbal products would be recommended for the treatment of PN and or muscular wasting. I am particularly interested in NAC, LAC and Q10 as treatments. Are there known doses of these products that are recommended?

Response from Dr. Moyle

This list was recently published in the Journal AIDS. None of them have any proven efficacy but are used by mitochondria, the organelle injured in neuropathy. Regards Graeme Moyle

alpha-lipoic acid 10 mg/kg/day Biotin 0.05 mg QD or BID L-carnitine 50-200 mg/kg/day Coenzyme Q10 (ubiquinone) 3.5-4 mg/kg/day Dichloroacetate 25-50 mg/kg/day Folate 0.4 mg QD or BID N-acetyl-cysteine 200 mg/kg/day Pantothenic acid 50 mg QD or BID Vitamin B1 (thiamine) 50-300 mg QD or BID Vitamin B2 (riboflavin) 30-400 mg QD or BID Vitamin B3 (niacin) 50 mg QD or BID Vitamin B6 (pyridoxine) 50 mg QD or BID Vitamin B12 (cyanocobalamin) 0.05 mg QD or BID Vitamin C 25 mg/kg/day Vitamin E 25 IU/kg/day Vitamin K3 (menadione) 20-500 mg/day Zinc picolinate 30 mg QD or BID


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