Advertisement
Professionals >> Visit The Body PRO
The Body: The Complete HIV/AIDS Resource
Sign up for free e-mail updates!The Body en Espanol
Home Page for TheBody.com, the Complete HIV/AIDS Resource What's New About HIV Ask the Experts About HIV Connect With Others About HIV Just Diagnosed With HIV HIV Treatment HIV Prevention Living With HIV Personal Stories of People With HIV All Topics Relating to HIV
Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.

Ask the Experts about Lipodystrophy and Wasting
  • E-mail E-Mail
  • Glossary Glossary

 

Videx EC
Jun 7, 2004

Hello Dr Moyle, I am currently on a Sustiva, Epivir, Videx EC regimen after switching from Zerit to Epivir 9 months ago. Does Videx EC contribute to facial wasting? I had moderate facial wasting on Zerit and have not seen any improvement switching to Videx EC. Should I continue taking Videx EC along with Epivir and Sustiva? Is this a good combination for facial fat recovery? Mike

Advertisement
   Response from Dr. Moyle

The answer appears to be no. In the FTC301 trial a combination of FTC/ddI/Efavirenz was associated with fat gain and an increase in waiste-hip ratio over 1 year where as the reverse was seen in the group taking d4T/ddI/Efavirenz. This suggests the problem is the thymidine analog, especially d4T, and that ddI (and efavirenz and FTC) are not diectly involved. There have not been any formal studies of switching to ddI based regimens to assess if lipoatrophy inproves after the switch

I would stick with this new combination for now..it is easy to take and should help some fat to recover over time

Kind Regards

Graeme Moyle


Want to read more questions and answers on this subject? Our experts have answered many similar questions!



Terms of Use
Please remember that this forum is designed for educational purposes only, and experts are not engaged through this forum in rendering legal or medical advice or professional services. Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither The Body nor any sponsor is the publisher or speaker of posted visitors' questions or the experts' material.

Questions and messages posted to this forum are not statements of advice, opinion, or information of The Body, Body Health Resources Corporation or any sponsor of this forum. While neither The Body nor Body Health Resources Corporation regularly reviews posted content, we reserve the right to delete, move, or edit postings if we deem it appropriate under the circumstances. Visitors submitting questions remain solely responsible for the content of their messages.

Information provided by experts is general only and should not be used for diagnosing or treating a health problem or a disease, or relied upon as legal or other professional advice. This information is not a substitute for professional advice or care. If you have or suspect you may have a health or legal problem, you should consult your own health care provider or your attorney.

Copyright notice.

global Toolbox
Learn more
Advertisement