Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.
|
|
 |  |
 |
 |
HAART Combos
May 20, 2004
What do u think about d4t, ddi, and kaletra as a combo?
I'm concerned about the D drugs and their side affects, ie face and neuropathy
Thanks
Michael
|
 |
|
Advertisement
Response from Dr. Moyle
Regimens of d4T/ddI are no longer recommended based on data that suggest they may be less effective and more toxic that alternative regimens. Preferred alternative regimens include tenofovir/FTC and abacavir/3TC both of which can be given once daily. Kaletra taken as 3 pills BID is often associated with lipid, especially triglyceride, elevation and some PIs are associated with an increased relative risk of fat loss. The more compact atazanavir/ritonavir combination is just 3 pills once daily and appears more fat friendly or if you would consider an NNRTI agent, efevirenz is the one most recommended in treatment guidelines and well supported by clinical trials data.
Kind regards
Graeme Moyle
Want to read more questions and answers on this subject? Our experts have answered many similar questions! |
|
|
 Please remember that this forum is designed for educational purposes only, and experts are not engaged through this
forum in rendering legal or medical advice or professional services. Experts appearing on this page are independent and are solely responsible
for editing and fact-checking their material. Neither The Body nor any sponsor is the publisher or speaker of posted visitors' questions or the experts' material.
Questions and messages posted to this forum are not statements of advice, opinion, or information of The Body, Body Health Resources Corporation or any sponsor of this
forum. While neither The Body nor Body Health Resources Corporation regularly reviews posted content, we reserve the right to delete, move, or
edit postings if we deem it appropriate under the circumstances. Visitors submitting questions remain solely responsible for the content of their
messages.
Information provided by experts is general only and should not be used for diagnosing or treating a health problem or a disease, or relied upon as
legal or other professional advice. This information is not a substitute for professional advice or care. If you have or suspect you may have a
health or legal problem, you should consult your own health care provider or your attorney.
Copyright notice.
|
|
Advertisement
|
|
E-Mail
Glossary
