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Ask the Experts about Lipodystrophy and Wasting
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change of meds
Feb 26, 2004

Thanks Dr. Moyle for answering my previous question. As I said before, I was diagnosed HIV+ in 1993 and have tried many of the meds in the market. I am taking Sustiva and Trizivir for some time now, however my T-cells are decreasing (112), and viral load increasing (80,632). My triglicerides is also high now (1176), so I started taking Tricor. My doctor and I are exploring new meds in order to put my number under control. I really never experienced opportunistic infectious or side effects besides facial lipodystrophy. I am also resistant to most of the meds, for example: Epivir, Retrovir, Efavirenz, Nevirapine, Ritonavir, Lopinavir... My doctor plans to put me on T-20 (injection), Lexiva, Norvir, Veriad, Ziagen and Epivir. I am just worried if these medications will increase my facial lipo and my triglicerides. My doctor also explored with me the option of a clinical trial with Titranevir in addition to T-20 and some of the other meds I mentioned above. What do you think would be my best options taking in consideration the information I provided you. I really appreciate your time and attention to this question. Thanks!

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   Response from Dr. Moyle

Certainly the number one priority is to get the right combination to control the virus. However, this combo also looks like a reasonable choice for limiting the risk of progression of the facial wasting. good luck regards Graeme Moyle



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