Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.
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Weaning off Oxandrin
Jul 10, 2003
Dear Doctor;
What would be the best way to wean myself off of Oxandrin. I am currently taking 20 mg per day (10 mg twice daily). I have been taking it for almost two years and would like to see how I am able to do if I lower the dose. It was prescribed by my HIV specialist for wasting, but my weight hasn't come up during the time on the medication. In fact, I weigh about 8 pounds less than I did when I began therapy almost two years ago, although I eat a tremendous amount of food. Your comments would be appreciated.
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Response from Dr. Moyle
It's a good plan to get off a drug that isn't helping and may be doing harm.
Withdrawal symptoms include mood swings, fatigue, restlessness, loss of appetite, insomnia,reduced sex drive, and depression. There are no clear protocols that I know about for discontinuation other than to stop and monitor. Using a testosterone gel may help reduce symptoms but ultimately one has to wait for the natural production of sex hormones resumes...this is generally thought to take 6 weeks or so.
Perhaps you should discuss with your doctor whether your HIV medications may be playing a role in weight loss and also talk to a dietitian about what may be done in your diet and exercise programme to help.
Good luck
Graeme
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