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stopping combo therapy when undectable???
Oct 7, 1998

i was reading a article that the NIH and others plan studies to test the possibility of stopping combo therapy in people with hiv who have been able to drastically reduce there vloads and maintain them under the level of detection ?Richard Chassion an aids researcher at John Hopkins university school of medicine raised the issue on an online presentation last week on the first day of the presentations at the Interscience Conference on Antimicrobial Agents and Chemotherapy he noted that mass.researcher Bruce Walker about one patient who began treatment before devoloping antibodies and stopped therapy.

Response from Dr. Holodniy

I think that type of patient presents a very different scenario than chronically infected HIV people with who had high viral loads which went below 50 copies with therapy. Infectious virus can still be cultured from lymph nodes and blood cells from such people. In addition, if therapy is stopped, we do in fact see a rebound in viral load. MH



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