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p-24 antigen question

Sep 11, 2001

Is the p-24 antigen positive for all the subtypes of hiv-1? If so, could someone eliminate the possibility of infection with these other subtypes by testing negative on the p-24 test, soon after possible infection/

Response from Dr. Holodniy

P24 antigen is pretty much the same in all viral strains. It unfortunately is very transient in nature. Unlike HIV antibodies and viral load, which are detectable consistently over time, p24 antigen is present only for a few days to weeks after acute infection.



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