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wildtype virus
Sep 11, 2001

Dr H., Great site! Thanks for all your "overtime" answering these questions. Getting tired of the worried wells "window period" and extremely "low risk" questions however.

My question: "If a patient acquires a highly divergent HIV strain abroad which fails to be detected/amplified by standard (type M) US commercial tests, will the production of "wild virus" within the patient increase detection possibilities using the same standard US commercial tests (bDNA, assay, PCR RNA, etc)?

Could you briefly explain "wild virus" as related to HIV?

Thank You!

Response from Dr. Holodniy

Wildtype virus is generally used to discuss viral strains without resistance mutations. Wildtype virus could be any subtype of HIV virus. Essentially all strains from abroad would be detected by most commercial assays.



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