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P24 antigen vs antibody.

Jan 28, 1999

Thank you very much for you work in this forum. You have the best and the most responsive web page.

If a person is infected with HIV virus, prior to seroconvert (before antibody is developed) the p24 antigen test will always show positive. In another words, the p24 antigen protein always exists unless the antibody is produced.

Response from Dr. Holodniy

Thanks for the kudos. Yes p24 antigen will always be positive prior to seroconversion. But..It will be declining as antibodies develop, and can rarely be gone before the antibody test is positive. Viral load will be positive throughout this process. MH

Viral structure

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