Antibody negative, high viral load
Mar 15, 1999
Dr. Holodniy, You answered a posting on March 5 in which you said that there have been cases where people were antibody negative but had high viral loads. Were these people in the window period (up to 6 months) before antibodies appeared and did they subsequently develop antibodies? Have many cases been documented of people who never develop antibodies? Thanks!
Response from Dr. Holodniy
No, these were people that were relatively advanced and apparently never developed antibodies. They were all positive by viral load, PCR or culture. This number is probably less than 10. There is early literature (late 80's)about delayed seroconversion which was described to take as long as 3-4 years. These people were all PCR positive from very early on (the exact time of the first sample varied between people). That data has since not been replicated, probably because the tests are so much more sensitive now than 10 years ago. MH
Get Email Notifications When This Forum Updates or Subscribe With RSS
- How Likely Is It To Get AIDS From Unprotected Anal Sex Without Ejaculation?
- How Likely Is It To Get HIV From Blowjob?
- Is It Possible To Get HIV From Genital Rubbing?
- Odds Of Getting HIV Performing Oral Sex
- Oral Sex With No Protection And HIV Transmission Risk
- Sex With Sex Worker Worried I Have AIDS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.