|what does undetectable really mean
Apr 19, 1999
what does undetectable really mean
what is normal cd-4 count
| Response from Dr. Holodniy
Undetectable means that the viral load is below the lower detection limit of the assay being used. The first generation assays, undetectable meant < 500 copies of virus/ml. In the new ultrasensitive viral load assays, undetectable means < 50 copies/ml. This does not mean 0. Although a few labs have created ultra, ultra sensitive assays ( down to 1 theoretical copy/ml) and in some patients cannot detect any virus in the plasma. Even with undetectable plasma viral load, the virus still exists inside cells, either in the blood, lymph nodes or semen. A normal CD4 count ranges from about 750-1500, with a 1,000 being about in the middle.
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