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PCR RNA / Antibodies
May 10, 1999

Hi doc.

Have read that a person can have PCR RNA test result < 50 copies / ml. and still be HIV Positive.

If this is a result for the immune system's ability to control viral replication - would this meen that immune system when "fighting the virus" would produce antibodies??

Is it possible to test negative both antibodies and RNA and still be HIV positive?

Response from Dr. Holodniy

There are a few people who have viral loads of < 50/ml, in the absence of therapy. They would indeed by people who had good immunologic control of the virus (antibodies and cytotoxic T cells). Although people keep hoping to find these cases, I have not heard or or personally seen a case of someone who is infected and has all these negative tests.

MH



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