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May 20, 1999

Dear Mark what is ecchymosis . How is it associated with HIV and would a cbc with plattlet count and bleeding time pick this up in this disease . Thanx again

Response from Dr. Holodniy

Eccymosis is essentially bruising. It is a nonspecific finding related in part to platelet count and function and clotting factors in the blood. The tests you mention can help determine if there is a defect with platelets. It can be related to HIV disease, usually late in the course, where the virus or other associated infections have destroyed cells in the bone marrow which make platelets. MH

one false positve unacceptable
What are neuro symptoms?

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