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Viral Load in HIV-1 and HIV-2
Aug 26, 1999

If someone is infected with HIV-2, will a viral load show show in an RNA PCR HIV-1 test? I am going over my husband's HIV test results and I am very confused on them stating that he definitely doesn't have HIV. He had a postive HIV-1 EIA, an indeterminate HIV-1 Western Blot (p-24), an HIV-1 RNA PCR viral load of 199 (ref. range <25). A week after his RNA PCR, he was given another HIV-1 EIA which resulted in negative. The physician concluded that he definitely doesn't have HIV and does not need to retest considering the low viral load result. These were all HIV-1 tests. If by chance he's infected with HIV-2, would any of these HIV-1 results reflect a positive, especially in a viral load count? Thank-you.

Response from Dr. Holodniy

NO. These tests are all specific for HIV-1.

MH



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