thymidine associated mutations
Oct 5, 1999
Are there any mutations in HIV RT which confer resistance to both of the thymidine nucleoside analogue RTIs (AZT and d4T)? Is the term thymidine associated mutation (TAM) one that has meaning to HIV physicians?
Response from Dr. Holodniy
Yes there are. Although AZT specific mutations don't confer resistance to d4T, a mutation at codon 151 along with a couple of others and an insertion of two amino acids at codon 69 among some other changes, confers class resistance to the nucleoside analogues (AZT, d4T type drugs). TAM would probably not have meaning to most physicians. MH
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Is Pain In Penis A Symptom Of HIV?
- Chills After Blowjob Worried I Have HIV
- Dry Cough After Insertive Anal Sex Without Condom Does It Mean I Have HIV
- Fever After Receptive Anal Sex With Condom Does It Mean I Have HIV
- HIVpain In Penis After Touching Dried Blood Sign Of HIV AIDS
- Stinging Pain After Insertive Anal Sex With Condom Does It Mean I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.