Sir - I recently went to a Dr. (for a rash) and had an HIV test done. I spoke w/Dr. today, as I tested positive for HIV on the initial test. She (Dr.) said the 1st test showed pos. but the 2nd HIV test was 'undetermined'. I do have lupus and am wondering if my having lupus would effect the HIV test results. If so-how much? I see the doc on Mon. but wish to ask you this for a little peace of mind over the weekend. Thank you for your time and attention. Happy St. Patrick's Day - Liz

Since lupus results in the production of several different autoimmune antibodies, it is possible this could result in a false positive HIV test. When HIV testing is done, the first test is usually a screening antibody test. If this test is positive, then a more specific test for HIV called the western blot is done. I assume this was the second test that was performed. An indeterminate western blot usually indicates that some, but not all the required antibodies for HIV infection are present. Therefore the test cannot be called truly positive. It is much rarer, although possible to have a false positive western blot. Usually indeterminate western blots are seen in people who are very recently infected, and have not developed all the different antibodies to HIV yet. In your case a repeat test is required. MH