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Decreasing t-cells, decreasing viral load
Jun 30, 2001

My husband's blood work just came back and in 7 months, his viral load dropped from 23,700 down to 7,300. But his t-cells went from 349 down to 288. Help/Suppress RTO also dropped from .35 down to .22 Should he be concerned about these changes or is it more important to focus on the viral load decreasing. He's been feeling pretty good, just a little fatigued (but I think that's more that he works too much!). Any suggestions??? I'm just a little concerned.

Response from Dr. Holodniy

You don't indicate whether he is receiving HIV specific treatment. If he is not on any treatment, I would be concerned about his decreasing CD4 count and ratio. A drop from 22 to 7,000 could just be assay variability. I would recommend starting treatment. If he is on treatment then the CD4 numbers are also going in the wrong direction, and the viral load should have decreased much further by this time. MH



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