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can HIV cause thinner blood vessel?

May 8, 2000

Dear Dr, I'm a doctor from Asia. I have a patient who is infected 20 months ago.Till now , he still does not take any anti-hiv medicine. I noticed that, his blood vessel in both arms are becoming much thinner than that of one year ago. The patient also have yellow color urine in recent 3 months. Do you think that HIV can cause these problems? Thanks!

Dr. chua

Response from Dr. Holodniy

I am not aware of HIV causing vessel thinning. However, numerous reports are present in the literature of HIV associated large and small vessel vasculitis. Whether HIV is causal is not clear. Their are some in vitro studies suggesting that HIV specific proteins can affect vascular permeability and that vascular associated immune cells are associated with the inflammatory process. MH

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