Jun 12, 2000
Dear Mark: I have had two occasions over the past two years where my VL has increased over UD and returned to undetectable. The first time was last March (88) and then last month (55). My CD4 have increased each time and last month was at an all time high of 501 (18%). I am extremely compliant with all of my medications and NEVER miss a dose (Sustiva/Combivir). My physician always discounts any value less than 100. Is that a safe assumption and is that considered normal test error? Thanks for all of your help!
| Response from Dr. Holodniy
Most of us are discounting these "blips" as noise in the assay. There is some variability in assay performance. However, they could be the result of intercurrent illnesses, nonadherence (doesn't sound like that in your case), or possibly resistant strains lurking in the background. Some very preliminary data demonstrated the presence of new resistance mutations in the cells of patients who had experienced these blips. I am advising my patients to hold the course and not consider any intensification of treatment until more data is collected to determine if these blips are clinically significant.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- How Do You Know If You Have Oral Thrush?
- Odds Of Contracting HIV Blowjob From A Prostitute
- Bloody Pee After Blowjob Worried I Have HIV
- Pain In Penis After Foreplay Does It Mean I Have HIV
- Painful Urination After Insertive Anal Sex Without Condom Does It Mean I Have HIV
- Red Spots After Anal Sex Worried I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.